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Diyala Journal for Pure Science

Scientific Refereed Journal Published By College of Science - University of Diyala


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Diyala Journal for Pure Science DJPS


P- ISSN:2222-8373, E-ISSN:2518-9255

Volume 15, Issue 3 , July . 2019





Synthesis of 2-Amino-5-Mercapto-1,3,4-Thiadiazole Derivatives and Evaluation of their Biological Activity


Khaled M. Matne, Hussein R. Hammod, Tahseen Ridha Ali , Wassan B. Ali


Year: 2019, Volume: 15, Issue: 3


Pages: 54-69 , DOI: https://dx.doi.org/10.24237/djps.15.03.483D


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In this work, new compounds, (S1-S17) were synthesized through the reaction of 5-amino-1,3,4-thiadiazole-2-thiol with different aromatic aldehyde by using fusion method. The newly synthesized compounds were confirmed by FT-IR-spectra and 1H-NMR, the biological activity of some new compound tested in vitro, against some bacterial positive and negative


Key words: 5-amino-2-mercapto-1,3, 4-thiadiazole, Schiff Base, Fusion method, Biological activity.

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